Fig. 2

Histopathological aspects of case 1. Biopsy of the lateral border of the tongue. Histological section stained with hematoxylin and eosin (HE), showing mucosa covered by hyperparakeratinized squamous epithelium, with the presence of an ulcer. There is a subepithelial “band” of intense inflammatory infiltrate (A). At higher magnification, lymphocyte exocytosis, hydropic degeneration of the basal layer, and Civatte bodies (black arrows) are observed (B). Perivascular inflammatory infiltrate (white arrows) (C)