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Table 2 The prognostic impacts on overall survival of two different early recurrence timepoints and different early recurrence definitions under diverse choices of chemotherapy patterns

From: Early recurrence as a pivotal event in nasopharyngeal carcinoma: identifying predictors and key molecular signals for survivors

Variables

HR (95% CI)

p-value

ER24 vs. Reference

12.330 (9.476–15.184)

< 0.001

ER36 vs. Reference

8.704 (6.260-11.148)

< 0.001

ER24 analysis

  

Population with inducing chemotherapy

12.249 (9.288–15.210)

< 0.001

Population with concurrent chemotherapy

8.842 (5.401–12.282)

< 0.001

Population with adjuvant chemotherapy

11.926 (3.112–20.741)

0.009

ER36 analysis

  

Population with inducing chemotherapy

11.177 (7.865–14.488)

< 0.001

Population with concurrent chemotherapy

5.556 (2.667–8.444)

< 0.001

Population with adjuvant chemotherapy

5.833 (-2.054-13.719)

0.148

  1. ER24, early recurrence within 24 months after radical radiotherapy; ER36, early recurrence within 36 months after radical radiotherapy