Table 5 Univariate and Multivariate logistic regression analysis for predicting the malignancy on biopsy in patients with benign or unsatisfactory fine-needle aspiration (FNA) results

Age

0.99 (0.97–1.02)

0.66

1.01 (0.98–1.04)

0.55

Sex (ref = male)

0.65 (0.32–1.3)

0.22

0.7 (0.31–1.55)

0.37

DM

0.59 (0.2–1.73)

0.33

0.66 (0.19–2.29)

0.51

HTN

0.74 (0.35–1.55)

0.42

0.96 (0.38–2.43)

0.93

Diameter

0.98 (0.72–1.34)

0.9

0.96 (0.65–1.43)

0.85

Location (ref = Superficial)

 Deep

1.03 (0.29–3.7)

0.97

0.51 (0.11–2.39)

0.39

 Whole

0.69 (0.31–1.53)

0.36

0.43 (0.16–1.2)

0.11

Multiplicity (ref = Single)

 Two

0.61 (0.14–2.69)

0.51

0.94 (0.2–4.48)

0.94

 More than Two

1.5 (0.32–7.07)

0.61

3.66 (0.65–20.5)

0.14

Enhancement (ref = Homogeneous)

 Heterogeneous

2.22 (0.82–6.96)

0.12

 Subtle

0.54 (0.1–2.92)

0.48

Shape (ref = Regular)

 Irregular

5.04 (2.46–10.31)

< 0.01*

3.06 (1.16–8.04)

0.02

Margin (ref = Well-defined)

 Ill-defined

3.99 (1.85–8.63)

< 0.01*

2.14 (0.79–5.85)

0.14

 Infiltrative

19.35 (3.05-122.59)

< 0.01*

1.09 (0.06–18.63)

0.95

Cystic

0.72 (0.35–1.48)

0.37

Lobulated

0.56 (0.26–1.21)

0.14

Invasion

12.02 (3.07–47.09)

< 0.01*

12.73 (1.27–127.4)

0.03

Calcification

0.65 (0.18–2.37)

0.52