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Table 3 Results of univariate meta-regression analysis

From: Circulating level of growth-differentiation factor 15 and the functional outcome after acute ischemic stroke: a systematic review and meta-analysis

Variables

OR for the association circulating GDF-15 and functional outcome after AIS

Coefficient

95% CI

p values

Adjusted R2

Publication year

0.071

-0.011 to 0.153

0.11

27.4%

Sample size

-0.00015

-0.00046 to 0.00015

0.28

2.9%

Mean age (years)

-0.036

-0.090 to 0.017

0.16

19.5%

Men (%)

-0.012

-0.064 to 0.040

0.62

-11.3%

Cutoff value of GDF-15 (ng/L)

-0.00045

-0.00123 to 0.00033

0.22

8.4%

Cutoff mRS of poor functional outcome

0.45

-0.18 to 1.09

0.14

18.7%

NOS

-0.19

-0.42 to 0.04

0.10

28.3%

  1. GDF-15, growth differentiation factor 15; AIS, acute isckemic stroke; OR, odds ratio; CI, confidence interval; mRS, modified Rankin Score; NOS, Newcastle-Ottawa Scale