Variables | COA (Mean ± SD) | SFA (Mean ± SD) | P-value | |||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
T0 | T1-T0 | T2-T0 | T2-T1 | T0 | T1-T0 | T2-T0 | T2-T1 | T0¶ | T1-T0£ | T2-T0£ | T2-T1£ | |
ESS | 6.5 ± 3 | 1.7 ± 2.5 | 0.1 ± 3.3 | -1.6 ± 4.6 | 8.3 ± 1.9 | 0.1 ± 2.7 | -0.1 ± 3.3 | -0.2 ± 3.3 | 0.13 | 0.35 | 0.26 | 0.79 |
SBQ | 0.7 ± 0.8 | 0.1 ± 0.6 | 0.3 ± 0.5 | 0.1 ± 0.6 | 1 ± 0.5 | -0.2 ± 0.4 | -0.3 ± 0.7 | -0.2 ± 0.4 | 0.26 | 0.71 | 0.21 | 0.71 |
Total sleep time (minutes) | 397.4 ± 51.6 | 2.2 ± 130.6 | -8.1 ± 50.5 | -10.3 ± 126.6 | 398.3 ± 49.9 | -18.9 ± 48 | -53.6 ± 67.6 | -34.7 ± 52.9 | 0.97 | 0.85 | 0.09 | 0.34 |
Total AHI (events/h) | ||||||||||||
 All | 3 ± 1.9 | 1.6 ± 2.5 | 0.2 ± 1.3 | -1.3 ± 2.8 | 3.9 ± 1.7 | 2.5 ± 4.2 | 0.3 ± 1.9 | -2.2 ± 4.6 | 0.20 | 0.18 | 0.16 | 0.43 |
 REM | 5.2 ± 2.1 | 1.5 ± 3.6 | 1 ± 4 | -1.5 ± 5.6 | 5.7 ± 3.4 | 3.6 ± 9.3 | 0.1 ± 3.1 | -3.3 ± 8.2 | 0.68 | 0.90 | 0.55 | 0.79 |
 NREM | 2.4 ± 1.9 | 2 ± 2.2 | -0.2 ± 1.6 | -2.3 ± 2.6 | 3.1 ± 2 | 1.3 ± 3.1 | 0.3 ± 2.1 | -0.9 ± 3.5 | 0.40 | 0.97 | 0.37 | 0.83 |
ObsAHI (events/h) | ||||||||||||
 All | 3 ± 2 | 1.2 ± 2.4 | 0.2 ± 1.3 | -1.1 ± 2.7 | 3.5 ± 1.7 | 2.5 ± 3.8 | 0.1 ± 1.7 | -2.4 ± 4.2 | 0.29 | 0.21 | 0.28 | 0.08 |
 REM | 5.2 ± 2.2 | 1.1 ± 3.5 | 0.9 ± 4.3 | -1.3 ± 6.1 | 5 ± 3.5 | 4 ± 9.4 | -0.2 ± 3.4 | -4.3 ± 8.1 | 0.92 | 0.90 | 0.77 | 0.84 |
 NREM | 2.4 ± 2 | 1.7 ± 2 | -0.3 ± 1.4 | -2 ± 2.2 | 2.9 ± 1.9 | 1.2 ± 2.5 | 0.3 ± 1.9 | -0.9 ± 3.2 | 0.50 | 0.90 | 0.52 | 0.99 |
ODI (events/h) | ||||||||||||
 All | 0.8 ± 0.8 | 0.6 ± 1.3 | 0.5 ± 1.7 | -0.1 ± 1.7 | 2.4 ± 3.7 | 0.5 ± 1.9 | -0.3 ± 0.7 | -0.8 ± 1.5 | 0.22 | 0.26 | 0.57 | 0.15 |
 REM | 1.7 ± 2 | 0.8 ± 2.3 | 1.1 ± 3.8 | 0.3 ± 2.7 | 4.3 ± 8.3 | 3.6 ± 4.6 | -2 ± 3.7 | -5.3 ± 7.2 | 0.47 | 0.65 | 0.67 | 0.66 |
 NREM | 0.7 ± 0.6 | 0.8 ± 1.3 | 0.1 ± 1.5 | -0.6 ± 1.5 | 1.8 ± 2.6 | -0.3 ± 1.8 | 0.1 ± 0.8 | 0.4 ± 2 | 0.20 | 0.58 | 0.58 | 0.84 |
Oxygen saturation (%) | ||||||||||||
 Mean | 96.4 ± 0.8 | -0.3 ± 0.7 | -0.1 ± 0.7 | 0.2 ± 0.6 | 96.3 ± 1.2 | -0.4 ± 1.1 | 0.1 ± 1.5 | 0.5 ± 1.5 | 0.60 | 0.61 | 0.10 | 0.16 |
 Minimum | 90 ± 3 | -4.6 ± 6.7 | -1.7 ± 3.5 | 2.9 ± 7.9 | 90.8 ± 3.6 | -4.5 ± 6.5 | -0.8 ± 4.7 | 3.7 ± 6.5 | 0.59 | 0.80 | 0.41 | 0.90 |
 <90 | 0 ± 0 | 0 ± 0 | 0 ± 0.1 | 0 ± 0.1 | 0 ± 0.1 | 0 ± 0.1 | 0 ± 0.1 | 0 ± 0.2 | 0.51 | 0.92 | 0.99 | 0.96 |
 <88 | 0 ± 0 | 0 ± 0 | 0 ± 0.1 | 0 ± 0 | 0 ± 0.1 | 0 ± 0.1 | 0 ± 0 | 0 ± 0.1 | 0.32 | 0.79 | 0.88 | 0.90 |
Pulse rate (bpm) | ||||||||||||
 Mean | 63.3 ± 7.9 | 6.5 ± 8.6 | -0.3 ± 3.6 | -6.8 ± 9.1 | 60 ± 8.8 | 3 ± 4.9 | 4.1 ± 3.8 | 1.1 ± 6.3 | 0.39 | 0.85 | 0. 10 | 0.34 |
 Minimum | 45.3 ± 9 | 6.1 ± 8.2 | 1.3 ± 5.9 | -4.8 ± 7.7 | 46.1 ± 8.9 | 0.8 ± 9.4 | -2.4 ± 8.6 | -3.2 ± 7.8 | 0.84 | 0.19 | 0.17 | 0.79 |
 Maximum | 105.9 ± 12.4 | 3.2 ± 12.7 | -1.6 ± 14 | -4.8 ± 10.7 | 98.4 ± 8 | 5.7 ± 11.2 | 4.9 ± 8.2 | -0.8 ± 8.9 | 0.12 | 0.66 | 0.50 | 0.80 |
Position (Sleep%) | ||||||||||||
 Supine | 63.7 ± 27.1 | 16.6 ± 15.3 | 3.6 ± 30.3 | -13 ± 32.6 | 60 ± 40.4 | 15.3 ± 23.2 | -4.2 ± 48.4 | -18.6 ± 50 | 0.82 | 0.70 | 0.99 | 0.88 |
 Non-supine | 35.6 ± 27.4 | -16.3 ± 15.8 | -3.4 ± 30.6 | 13 ± 33 | 39.4 ± 40.6 | -14.9 ± 23.3 | 4.1 ± 49.1 | 18 ± 49.9 | 0.82 | 0.67 | 0.93 | 0.92 |
AHI (events/h) | ||||||||||||
 Supine | 2.5 ± 1.8 | 2 ± 2.8 | 0.9 ± 3.3 | -1.1 ± 4.5 | 2.6 ± 2.3 | 2.8 ± 4.2 | 0.6 ± 2.7 | -2.6 ± 5.1 | 0.89 | 0.21 | 0.76 | 0.25 |
 Non-supine | 2.2 ± 1.9 | 0.4 ± 4.1 | 1 ± 3.9 | 0.6 ± 5.7 | 3.4 ± 3 | -2.7 ± 3.2 | -1 ± 3.2 | 1.5 ± 3.1 | 0.30 | 0.49 | 0.26 | 0.72 |
ODI (events/h) | ||||||||||||
 Supine | 0.7 ± 0.6 | 0.7 ± 1.6 | 1 ± 2.5 | 0.3 ± 2.6 | 2.7 ± 4.7 | -0.1 ± 2.3 | -1.7 ± 5.1 | -2 ± 3 | 0.14 | 0.50 | 0.88 | 0.83 |
 Non-supine | 0.7 ± 1 | 0.2 ± 1.1 | 0.3 ± 2 | 0.2 ± 2.2 | 1.9 ± 2.6 | -1.7 ± 2.7 | 0 ± 1.6 | 1.3 ± 3.6 | 0.12 | 0.81 | 0.16 | 0.37 |
Snoring Level (dB) | ||||||||||||
 >40 (Sleep%) | 22.6 ± 26.6 | 21.6 ± 25.9 | -5.4 ± 23.8 | -27 ± 27.4 | 34.8 ± 36.7 | 2.8 ± 13.1 | -7.1 ± 46.8 | -6.3 ± 51.8 | 0.43 | 0.19 | 0.76 | 0.62 |
 >50 (Sleep%) | 1.8 ± 1.3 | 0.7 ± 1.7 | -0.5 ± 1.2 | -1.2 ± 1.8 | 1.7 ± 0.9 | 0.9 ± 2.7 | 0.5 ± 1.1 | -0.3 ± 3.3 | 1.00 | 0.90 | 0.32 | 0.54 |
 >60 (Sleep%) | 0.4 ± 0.2 | 0.1 ± 0.3 | 0.1 ± 0.3 | 0 ± 0.5 | 0.4 ± 0.3 | -0.1 ± 0.3 | 0.2 ± 0.3 | 0.2 ± 0.3 | 0.93 | 0.19 | 0.70 | 0.33 |
 TS (Sleep%)* | 3.4 ± 2.8 | 6.2 ± 10.7 | -0.9 ± 2.8 | -7.1 ± 11 | 3.4 ± 2.2 | 5.6 ± 9.6 | 1 ± 4.5 | -3.6 ± 12.3 | 0.73 | 0.24 | 0.32 | 0.57 |
 Mean | 40.6 ± 0.7 | 0.9 ± 0.9 | -0.1 ± 0.7 | -1 ± 1.3 | 40.8 ± 1 | 0.7 ± 1.3 | 0.3 ± 1.1 | -0.4 ± 2 | 0.80 | 0.84 | 0.92 | 0.94 |
Sleep (%) | 84.4 ± 5.5 | -3.3 ± 9.7 | 2.5 ± 6.9 | 5.8 ± 10.2 | 88.2 ± 6 | -4.2 ± 7.2 | -0.3 ± 5.5 | 4 ± 4.7 | 0.15 | 0.75 | 0.19 | 0.12 |
Sleep latency (minutes) | 18.2 ± 12.1 | 4 ± 17.8 | 0.9 ± 19.3 | -3.1 ± 18.5 | 18.7 ± 13.7 | 5.6 ± 29.6 | 1.1 ± 14.6 | -4.5 ± 22.1 | 0.93 | 0.64 | 0.88 | 0.66 |
REM latency (minutes) | 119.9 ± 74.6 | 1.3 ± 103.8 | -36.8 ± 77.6 | -38.1 ± 75.1 | 101.3 ± 52 | 2.9 ± 65.6 | -32.7 ± 57.4 | -35.6 ± 42.4 | 0.53 | 0.62 | 0.88 | 0.55 |
Number of wakes | 6.9 ± 3.3 | 0.9 ± 6.6 | -0.9 ± 4.7 | -1.8 ± 5.3 | 5.4 ± 5.1 | 1.5 ± 6.5 | 0.5 ± 3.2 | -1 ± 4.7 | 0.12 | 0.79 | 0.39 | 0.28 |
Sleep stage | ||||||||||||
 REM (%) | 25.7 ± 6 | -4 ± 13.2 | 0.7 ± 5 | 4.6 ± 10.4 | 25.7 ± 4.8 | -4.4 ± 8.9 | 4.7 ± 6.6 | 9.1 ± 5.5 | 0.97 | 0.69 | 0.38 | 0.95 |
 Light (%) | 52.8 ± 7.2 | 4.3 ± 15.3 | -2.5 ± 7.4 | -6.8 ± 12.1 | 54.9 ± 5.6 | 2 ± 6 | -7.7 ± 9.6 | -9.7 ± 7 | 0.47 | 0.50 | 0.44 | 0.39 |
 Deep (%) | 21.6 ± 3.4 | -0.4 ± 6.5 | 1.8 ± 4.9 | 2.2 ± 7.8 | 19.3 ± 5.2 | 2.4 ± 6.4 | 2.2 ± 7.5 | -0.2 ± 7.5 | 0.28 | 0.59 | 0.13 | 0.49 |